PT-141 (Bremelanotide): Central Nervous System Melanocortin Research

When researchers look to buy PT-141, they are seeking Bremelanotide, a synthetic heptapeptide analogue of $\alpha$ -melanocyte-stimulating hormone ( $\alpha$ -MSH). Unlike many related compounds that act on peripheral vascular systems, PT-141 is uniquely characterized by its centrally mediated activity. It serves as a potent agonist of melanocortin receptors, specifically targeting the MC3R and MC4R pathways primarily expressed in the hypothalamus. Procuring high-purity PT-141 peptide is critical for investigating the neurobiology of sexual motivation and the dopaminergic pathways that control arousal and desire.

Technical Specifications

Chemical Name: $N$ -acetyl-L-norleucyl-L- $\alpha$ -aspartyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl-L-lysine (2$\rightarrow$7)-lactam
Molecular Formula: $C_{50}H_{68}N_{14}O_{10}$ (free base)
Molecular Weight: 1025.2 g/mol
Purity: $\geq$ 99% (HPLC Tested)
Format: Lyophilized White Powder
Solubility: Soluble in water (up to 5 mg/ml in PBS) and organic solvents like DMSO
Storage: Store desiccated at -20°C for long-term stability

Research Applications: What is PT-141?

For those investigating the utility of this compound, PT-141 is at the forefront of studies involving sexual dysfunction and central appetite regulation. Researchers often buy PT-141 online to analyze its effects on the paraventricular and supraoptic nuclei of the brain. In animal models, administration has been shown to activate neurons in the hypothalamus, evidenced by increased c-Fos immunoreactivity, which leads to significant increases in sexual motivation and solicitation behaviors. Its mechanism provides a novel approach to treating hypoactive sexual desire disorder (HSDD) by targeting central motivation rather than peripheral blood flow.

Strategic Sourcing and Global Logistics

For laboratories searching to buy PT-141 near me or internationally, selecting a supplier that provides a verified 99%+ purity guarantee is essential to avoid synthesis artifacts that could compromise neurological assays. We offer secure international shipping to the USA, UK, Canada, and Australia, ensuring that your research materials are delivered with the stability required for sensitive behavioral studies. All vials are shipped as lyophilized powder, which is stable at room temperature for up to three weeks during transit but requires deep-freeze storage upon receipt.

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Intended Use:

This compound is intended strictly for in vitro laboratory research. It is not approved for human or animal administration and must not be used in food, dietary supplements, cosmetics, or pharmaceuticals.

Legal Disclaimer:

This product and related information have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, cure, or prevention of any disease. Use is restricted to qualified research professionals in certified laboratory environments.

Terms of Sale:

By purchasing from Mile High Compounds, the buyer affirms they are a qualified researcher or institution, fully responsible for lawful handling, storage, and research use of this material. All sales are final.